USES OF TRAMADOL IN VETERINARY MEDICINE

1. Tramadol is widely used in veterinary medicine, especially for treating pain in dogs.
2. It is often used to treat pain resulting from conditions like cancer, arthritis, and post-surgical inflammation in dogs. It has mild anti-anxiety properties, making it useful for reducing the skittishness that pain can often produce in animals.
3. Tramadol for dogs is often safer than using other pain medications, such as non-steroidal anti-inflammatory drugs like Tylenol, since it does not cause damage to the stomach or liver of canines.
4. Tramadol for dogs comes in both liquid, pill, powder, and ampule form. Often the medication must be mixed into food to be given to dogs, since it has an unpleasant taste.

FACTS OF TRAMADOL

1. Tramadol is in a group of drugs called opiate agonists. It is used to treat moderate to severe pain by changing the way the body senses pain.
2. Tramadol can either be taken as a normal tablet or an extended-release (long-acting) tablet to be taken through the mouth. The regular tablet can be taken with or without food every four to six hours or as needed. 
3. The extended-release tablet should only be taken once a day around the same time every day.
4. When using extended-release the patient either needs to always take it with food or always take it without food. 
5. The extended-release tablets should only be taken whole. It is dangerous to split, chew, crush, snort or inject the dissolved form of the tablet.
6. It is important to only take the medication as the doctor prescribes because it is a highly dependent drug.

WHY TRAMADOL?

•  Grünenthal established that Tramadol has a weak respiratory depressant effect when compared with morphine. it changes the way human body feels pain.
• Tramadol provides adequate pain relief in patients with different types of pain.
• Tramadol has many clinical trials have showed that is more effective than other analgesics in some particulars kinds of pain.
• Tramadol has many other trials have demonstrated the acceptable safety profile of a well administered dosage schedule of Tramadol in patients with low back pain and hip or knee osteoarthritis.

TRAMADOL - ADVANTAGES IN BRIEF

• generally well tolerated
• proven efficacy in a broad range of painful conditions
• respiratory depressionis less common and less pronounced than with other opioids 
• lesser constipation effect than with other opioids 
• withdrawal not considered to be as severe as that produced by other opioids
• low abuse and dependence potential 
• more effective than NSAIDs for controlling post operative pain
• antidepressant-like (mood improving) activity 
• local anesthetic activity 
• low interaction potential
• devoid of immunosuppressive activity
• reasonably priced - available generic formulation

HOW TO GET RID OF TRAMADOL ADDICTION?

• Your doctor's advice is the best way to prevent from the tramadol. 

• A popular way to overcome the addiction is the use of  the Waismann Method of Accelerated Neuro-Regulation program.

• This approach requires a stay in hospital for a few days, but is able to handle drug tramadol opioid receptors with the cleaning. 

• A healthy lifestyle in conjunction with the exercises and diet can help control the symptoms. 

• You can also reduce the dependence of tramadol by using the Ginko biloba , fish oil, green tea and vitamin b supplements. 

• In addition, your doctor may recommend counseling and drug treatment program for combating drug tramadol.

SYMPTOMS OF TRAMADOL DRUG ADDICTION

1. If you are addicted to tramadol and are trying to quit the habit, you may end up feeling withdrawal symptoms.
2. Symptoms can vary from moderate to very severe and includeTremors
   Anxiety
   Inability to sleep
   Sweating
   Diarrhea
   Hallucinations
   Pain.
   
3. It is recommended that you do not stop taking the medication abruptly.
4. You will need to gradually get off the drug in order to avoid withdrawal symptoms and not relapse.

TRAMADOL - SIGNS OF ADDICTION

• If a patient is using tramadol in a manner that is inconsistent with treatment, they are addicted to the drug. 
• Inconsistencies include taking higher dosages of the drug or taking tramadol more frequently then you are supposed to. 
• Other signs of addiction include a patient getting multiple prescriptions from different doctors to get more tramadol. 
• You may also be addicted if you are stealing tramadol or you are acquiring the drug from outside sources.

SIGNS OF TRAMADOL DEPENDENCY

1. Experts claim that there is a major difference in the definition of dependency and addiction. Patients who are dependent on the drug only use it because of a condition that is still being treated.
2. Patients who are self-medicating run a higher risk of dependency.
3. In some states, this drug can be purchased over the counter and is another reason for the abuse of tramadol.
4. There is also an increased chance of dependency if the patient is using tramadol for an extended amount of time. 
5. Many doctors report that the dependency for this drug is purely psychological and increased dosage may cause the user to become accustomed to the lessened pain.
6. Anything above the recommended dosage will cause side effects that can harm you. This drug is used to control pain and is not intended for other health conditions

TRAMAOL IS ADDICTIVE OR NOT?

• Tramadol is classified as a narcotic but is not a drug like morphine. 

• Many patients are weary of taking this drug due to its likelihood for addiction. 

• If tramadol is used as recommended, you will not become dependent or addicted to the drug.

• Many patients who use tramadol have claimed that the drug is addicting. 

• A recent study by the Journal of Family Practice found that tramadol has a low risk of addiction. 

• Tramadol is considered to be one of the better pain relievers that is available, but dependence can become an issue if prescriptions are not monitored.

PURPOSE OF TRAMADOL WHO USED IT

1. Generally speaking, people who need relief from pain are the ones who use Tramadol. 
2. This is a drug that goes into your body and slowly releases the pain-killing ingredients over a long period of time. These go to the nerve endings and change the way that you feel the pain, making it so that you are not in agony any longer.
3. Anyone who has felt enduring pain that will not abate on its own is a candidate for this type of a drug.
4. If you are looking for more specific examples, those exist as well. First off, people who have been hurt in car accidents often use Tramadol while they try to heal; this drug lets them sleep so that they can rest and get better. 
5. People who have had surgery will also use it if the surgery was rather invasive and left them with a long recovery time. 
6. People who are growing older and who have been injured through falls and other such accidents will also take this drug for their pain.

BENEFITS OF TRAMADOL

•	Relieves various causes of pain, including post-surgery pain
•	Used to treat chronic pain
•	Can be used with or as an alternative to non-steroidal anti-inflammatory drugs (NSAIDs)

OTHER DRUGS THAT AFFECT TRAMADOL IN PET ANIMALS

• Seizure will appear more if you give tramadol while giving certain other medications. 
• Tell your veterinarian if you are also giving your pet or using any of the following medications: 

1. an MAO inhibitor such as selegiline (Anipryl), Mitaban, or a Preventic Collar; an antidepressant such as amitriptyline, clomipramine (Clomicalm), fluoxetine (Prozac, Reconcile), or acepromazine.
2.  warfarin (Coumadin) 
3. digoxin (Lanoxin) 
4. ketoconazole (Nizoral) 
5. drugs that can cause drowsiness such as other pain medications, muscle relaxants, and herbal products.

• This list is not complete and there may be other medications that can interact with tramadol.

• Tell your veterinarian about all the prescription and over-the-counter medications you give your pet.

• This includes vitamins, minerals and herbal products.

TRAMADOL TABLET IMAGES

TRAMADOL ORAL TABLETS 50 Mg

TRAMADOL HISTORY

HOW TRAMADOL WORKS TO FIGHT AGAINST THE PAIN

              Pharmacology is one of the scientific areas that are involved in the drug discovery process. Its team of professionals is the one who check drug substances for physiological test because there is a difference between what substances do and how they act.

           
               The increase in chemical information has been the development of the modern pharmaceutical industry. The science of pharmacy appeared gradually from the conventional empiricism of the herbalist, but by 19th century there had been some important accomplishments in the study of existing drugs and in the design of innovative ones.

                If it is necessary to go on talking about history, it is time to offer some information about Pharmaceuticals. In 1231 Roman Emperor Fredrick II separated the pharmaceutical profession from the medical profession and at that moment medication history changed. In 1546 the first organized list of substances and medical chemicals appeared in Germany and pharmaceutical science achieved an important objective toward a better organization.                   Past events can help people to know more about the medications they take and it may be a good way of trusting them. Which was the first human concern about health? The relief of pain has been one of the main reasons for expansion of Health Care and Pharmacology.
                   Tramadol history is worth telling because this active ingredient is contained in many products that help to relieve pain and this fact is very important for suffering patients.
                   Once upon a time there was a big pharmaceutical company that decided to fight against pain that was being suffered by millions of patients all over the world. That big corporation is Grünenthal GmbH.
Grünenthal GmbH was founded in 1946 in German and it has been owned by a family (The Wirtz) since then. Their first objective was to produce medicines for the penniless German inhabitants after the Second World War. To manufacture their products they used medicinal herbs they cultivated on their leased land. In 1948, the company experienced an important event; Grünenthal brought the first penicillin medication on the market.
Grünenthal enlarged its product range by cooperation with other pharmaceutical companies and by performing its own researches. In 1962 Tramadol was born and Tramal® development started. After 15 years of uninterrupted investigation, Tramal® (Tramadol) was launched in 1977. This molecule revolutionized the painkiller market because it is different from other opioids, it has a double mode of action.
                         Grünenthal young Executive Board follows Wirtz family tradition but their modern vision about pharmaceutical business has improved the company in many aspects. They are eager to put a new philosophy for managers and employees. They want Grünenthal become a synonym of reliability, modernity, concern and professionalism.
                         The company is not alone in the struggle against disease. Grünenthal GmbH has signed licensing agreements with other companies (like Ortho-McNeil Pharmaceutical and Takeda) to research and develop high quality medicines and commercializes them in many countries.
                           This is only a part of the story. After the first Tramadol release, other companies started to market this drug with a wide range of brand names and different pharmaceutical forms.
                            The latest pharmaceutical news says that once-daily Tramadol was launched in Korea and Australia. It means that Tramadol has been also changed during the last 20 years. It has been improved to offer patients faster and better pain relief. Tramadol future will depend on how doctors and patients will use it and how pharmaceutical companies will improve this drug substance to make it the best in its category.
                           Tramadol has an important scientific background that enables this drug substance to help millions of patients all around the world and there is a family behind this active principle. Their major concerns are helping people who need medical support.
Life and health are precious treasures that people must take care of. Grünenthal GmbH has protected them since its foundation. For the company, science is the tool to improve people quality of life.
                           This history has been focused on the development of a pharmaceutical product. And it is not only associated with past; it is also the future of human health. Tramadol history does not have an end and this is a good thing.