CLINICAL RESULT OF TRAMADOL [ULTRAM]

• Ultracet has been evaluated for efficacy and safety in pivotal single-dose trials in subjects with acute pain.

•  In these trials, subjects with pain following oral surgical procedures who received two tablets of Ultracet experienced greater relief than placebo-treated subjects. 

• Additionally, subjects treated with Ultracet experienced greater relief than subjects on either of the individual components given at the same dose.

• The onset of pain relief after Ultracet (occurring in less than one hour) was faster than with tramadol alone, whereas the duration of pain relief after Ultracet was longer than with acetaminophen alone. Analgesia was found to be generally comparable to ibuprofen.