CONTRAINDICATIONS OF TRAMADOL

• ULTRAM® (tramadol hcl) should not be administered to patients who have previously demonstrated hypersensitivity to tramadol, any other component of this product or opioids.

• ULTRAM® (tramadol hcl) is contraindicated in any situation where opioids are contraindicated, including acute intoxication with any of the following: 

1. alcohol
2. hypnotics
3. narcotics
4. centrally acting analgesics
5. opioids or psychotropic drugs.

•  ULTRAM® may worsen central nervous system and respiratory depression in these patients.