TRAMADOL INJECTION - A COMPLETE VIEW

            Tramadol is a weak against at all types of opiod receptors with some selectivity for neuroreceptors. It is a good analgesic. But has little respiratory depression and GI effects. No drug dependence or tolerance to analgesic effects occurs.

Indications:
             Severe acute and chronic pain in diagnostic procedures and surgical pain, arthralgia, pain associated with fractures and osteoarthritis.

Dosage:

•   Oral :50-100 mg 2-3 times daily. Maximum 400mg divided doses . 

•    IV/IM/SC 100 mg Child 1.15 mg/kg Maximum 500 mg.

Adverse effects:

•   Sweating 

•    nausea 

•    vomiting 

•   animation 

•   dizziness.

Drug interactions:

            Concomitantly administered tranquillisers and other CNS depressants sedative effects potentiated. MAOI’s fatal interaction occurs opioid analgesics like buprenorphine, butorphanol ans pentazocine may precipitate with drawal symptoms.